RNH1 Rabbit Polyclonal Antibody (CAB4079)
- SKU:
- CAB4079
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | RNH1 Rabbit Polyclonal Antibody |
SKU: | CAB4079 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 202-461 of human RNH1 (NP_002930.2). |
Sequence: | EALK LESC GVTS DNCR DLCG IVAS KASL RELA LGSN KLGD VGMA ELCP GLLH PSSR LRTL WIWE CGIT AKGC GDLC RVLR AKES LKEL SLAG NELG DEGA RLLC ETLL EPGC QLES LWVK SCSF TAAC CSHF SSVL AQNR FLLE LQIS NNRL EDAG VREL CQGL GQPG SVLR VLWL ADCD VSDS SCSS LAAT LLAN HSLR ELDL SNNC LGDA GILQ LVES VRQP GCLL EQLV LYDI YWSE EMED RLQA LEKD KPSL RVIS |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | RAI; RNH; RNH1 |
Positive Sample: | Raji,U-87MG,HT-29,HeLa,Mouse liver,Mouse kidney,Mouse lung,Rat brain,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 50kDa |
Observed MW: | 43kDa |
Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.
Purification Method: | Affinity purification |
Gene ID: | 6050 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |