Description
RNH1 Monoclonal Antibody [PAT1H23AT] (CPAB0165)
The RNH1 Polyclonal Antibody (CPAB0165) is a vital tool for researchers studying RNH1, a key protein involved in RNA metabolism and DNA replication. This antibody, produced in rabbits, shows high specificity and sensitivity towards human samples, making it ideal for a range of applications, including Western blot and immunofluorescence.RNH1, also known as ribonuclease/angiogenin inhibitor 1, plays a crucial role in controlling RNA processing and preventing RNA degradation. Its involvement in DNA replication also makes it a target for cancer research and understanding genetic disorders.
By detecting and analyzing RNH1 protein levels, researchers can gain valuable insights into cellular processes and disease mechanisms.With its ability to effectively recognize and bind to RNH1, this antibody is a valuable tool for studying RNA metabolism, DNA replication, and related pathways. Its use in various cell types makes it a versatile option for researchers investigating gene regulation, cancer biology, and other fields related to molecular biology and genetics.
Product Name: | RNH1 Antibody |
Product Sku: | CPAB0165 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human RNH1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human RNH1 amino acids 7-461 purified from Ecoli. |
Clone: | PAT1H23AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA |
Purification Method: | RNH1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG2a |
Background: | RNH1 belongs to the proteinaceous cytoplasmic RNase inhibitors family which occur in many tissues and binds to both intracellular and extracellular RNases. In addition to control of intracellular RNases, the inhibitor may have a part in the regulation of angiogenin. The 50kDa RNH1 binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases possibly play a critical role in the turnover of RNA in eukaryotic cells, RNH1 may be vital for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo. |
Synonyms: | Ribonuclease inhibitor, Ribonuclease/angiogenin inhibitor 1, Placental ribonuclease inhibitor, Placental RNase inhibitor, RAI, RNH, MGC4569, MGC18200, MGC54054, RNH1, PRI. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |