RNF6 Rabbit Polyclonal Antibody (CAB14572)
- SKU:
- CAB14572
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | RNF6 Rabbit Polyclonal Antibody |
SKU: | CAB14572 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RNF6 (NP_898864.1). |
Sequence: | MNQS RSRS DGGS EETL PQDH NHHE NERR WQQE RLHR EEAY YQFI NELN DEDY RLMR DHNL LGTP GEIT SEEL QQRL DGVK EQLA SQPD LRDG TNYR DSEV PRES SHED SLLE WLNT FRRT GNAT RSGQ NGNQ TWRA VSRT NPNN GEFR FSLE IHVN HENR GFEI HGED YTDI PLSD SNRD HTAN RQQR STSP VARR TRSQ TSVN FNGS SSNI PRTR LASR GQNP AEGS FSTL GRLR NGIG GAAG IPRA NASR TNFS SHTN QSGG SELR QREG QRFG AAHV WENG ARSN VTVR NTNQ RLEP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | RNF6 |
Positive Sample: | DU145,U-87MG,Mouse testis,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Cytoplasm, Nucleus, PML body, axon. |
Calculated MW: | 78kDa |
Observed MW: | 78kDa |
The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.
Purification Method: | Affinity purification |
Gene ID: | 6049 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |