The RNF6 Polyclonal Antibody (CAB14572) is a vital tool for researchers studying the RNF6 protein, a key player in the regulation of various cellular processes. This antibody, produced in rabbits, exhibits high reactivity towards human samples and is validated for use in Western blot applications. By specifically binding to the RNF6 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and cancer research.RNF6, a member of the Ring Finger Protein family, is known for its involvement in the ubiquitination process, which plays a crucial role in protein degradation and signal transduction pathways.
By targeting RNF6, researchers can gain insights into the mechanisms underlying cell proliferation, differentiation, and survival. Additionally, aberrant expression of RNF6 has been linked to various diseases, including cancer and neurological disorders, highlighting its potential as a therapeutic target.By utilizing the RNF6 Polyclonal Antibody (CAB14572), researchers can further unravel the functions of RNF6 and its implications in disease pathology. Understanding the regulatory roles of RNF6 could lead to the development of novel treatment strategies for a range of conditions, paving the way for advancements in personalized medicine and targeted therapies.
Product Name:
RNF6 Rabbit Polyclonal Antibody
SKU:
CAB14572
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RNF6 (NP_898864.1).
The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.
Purification Method:
Affinity purification
Gene ID:
6049
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RNF6 Rabbit pAb (CAB14572) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
