The RNF5 Polyclonal Antibody (CAB8351) is a valuable tool for researchers studying the RNF5 protein, a critical player in the regulation of protein degradation and immune responses. This antibody, produced in rabbits, is highly specific to human samples and is validated for Western blot applications. By targeting the RNF5 protein, this antibody allows for the detection and analysis of RNF5 expression in a variety of cell types, making it ideal for studies in immunology and cancer research.
RNF5, also known as a ubiquitin E3 ligase, has been implicated in various cellular processes, including the regulation of immune signaling pathways and protein turnover. Its role in immune regulation makes it a promising target for research into diseases like cancer, autoimmune disorders, and inflammatory conditions. By understanding the function of RNF5, researchers can gain insights into potential therapeutic strategies that manipulate immune responses in these disease contexts.
Product Name:
RNF5 Rabbit Polyclonal Antibody
SKU:
CAB8351
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human RNF5 (NP_008844.1).
The protein encoded by this gene contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions.
Purification Method:
Affinity purification
Gene ID:
6048
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using RNF5 Rabbit pAb (CAB8351) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
