RNF40 Rabbit Polyclonal Antibody (CAB6443)
- SKU:
- CAB6443
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- IF
- IP
- ChIP
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | RNF40 Rabbit Polyclonal Antibody |
SKU: | CAB6443 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RNF40 (NP_055586.1). |
Sequence: | MSGP GNKR AAGD GGSG PPEK KLSR EEKT TTTL IEPI RLGG ISST EEMD LKVL QFKN KKLA ERLE QRQA CEDE LRER IEKL EKRQ ATDD ATLL IVNR YWAQ LDET VEAL LRCH ESQG ELSS APEA PGTQ EGPT CDGT PLPE PGTS ELRD PLLM QLRP PLSE PALA FVVA LGAS SSEE VELE LQGR MEFS KAAV SRVV EASD RLQR RVEE LCQR VYSR GDSE PLSE AAQA HTRE LGRE NRRL QDLA TQLQ EKHH RISL EYSE LQDK VTSA ETKV LEME TTVE DLQW DIEK LRKR EQKL NKHL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | BRE1B; RBP95; STARING; RNF40 |
Positive Sample: | MCF7,HepG2,U-937 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 114kDa |
Observed MW: | 130kDa |
The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 9810 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |