RNF4 Rabbit Polyclonal Antibody (CAB12037)
- SKU:
- CAB12037
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | RNF4 Rabbit Polyclonal Antibody |
SKU: | CAB12037 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human RNF4 (NP_001171938.1). |
Sequence: | MSTR KRRG GAIN SRQA QKRT REAT STPE ISLE AEPI ELVE TAGD EIVD LTCE SLEP VVVD LTHN DSVV IVDE RRRP RRNA RRLP QDHA DSCV VSSD DEEL SRDR DVYV TTHT PRNA RDEG ATGL RPSG TVSC PICM DGYS EIVQ NGRL IVST ECGH VFCS QCLR DSLK NANT CPTC RKKI NHKR YHPI YI |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | SLX5; SNURF; RES4-26; RNF4 |
Positive Sample: | Mouse kidney,Mouse brain,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, PML body, nucleoplasm. |
Calculated MW: | 21kDa |
Observed MW: | 21kDa |
The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.
Purification Method: | Affinity purification |
Gene ID: | 6047 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |