The RNF31 Polyclonal Antibody (CAB8227) is a valuable tool for researchers studying the RNF31 protein, also known as HOIP, which plays a crucial role in the regulation of immune responses and inflammation. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is optimized for use in Western blot applications. By binding specifically to the RNF31 protein, researchers can accurately detect and analyze its expression in a variety of cell types, making it an ideal choice for studies in immunology and cancer research.RNF31 is a key player in the immune signaling pathway, particularly in the regulation of NF-kB activation and cytokine production.
Dysregulation of RNF31 has been associated with various diseases, including autoimmune disorders, inflammatory conditions, and cancer. Understanding the function of RNF31 is essential for developing targeted therapies that modulate immune responses and inflammation in these disease settings.In summary, the RNF31 Polyclonal Antibody (CAB8227) offers researchers a reliable tool for studying the role of RNF31 in immune regulation and inflammation, providing valuable insights for the development of novel therapeutic strategies in a range of disease contexts.
Product Name:
RNF31 Rabbit Polyclonal Antibody
SKU:
CAB8227
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human RNF31 (NP_060469.4).
The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. The encoded protein is the E3 ubiquitin-protein ligase component of the linear ubiquitin chain assembly complex. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
55072
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RNF31 antibody (CAB8227) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
