The RNF24 Polyclonal Antibody (PAC029556) is a valuable tool for researchers studying RNF24, a protein involved in the regulation of cell proliferation and programmed cell death. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the RNF24 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it ideal for investigations in cell biology and cancer research.RNF24, also known as Ring Finger Protein 24, plays a crucial role in cellular processes such as DNA repair, signal transduction, and protein degradation.
Dysregulation of RNF24 has been linked to various diseases, including cancer, neurodegenerative disorders, and autoimmune conditions. Therefore, understanding the function of RNF24 is essential for the development of targeted therapies and diagnostic tools for these diseases.Overall, the RNF24 Polyclonal Antibody (PAC029556) is a valuable resource for scientists looking to explore the role of RNF24 in health and disease. Its high specificity and sensitivity make it a reliable tool for conducting innovative research in the fields of molecular biology and medicine.
Immunohistochemistry of paraffin-embedded human thyroid tissue using PACO29556 at dilution of 1:100.
Immunofluorescent analysis of HepG2 cells using PACO29556 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human lung tissue using PACO29556 at dilution of 1:100.
Background:
May play a role in TRPCs intracellular trafficking.
Synonyms:
RING finger protein 24, RNF24
UniProt Protein Function:
RNF24: May play a role in TRPCs intracellular trafficking. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Ubiquitin conjugating system; Membrane protein, integralChromosomal Location of Human Ortholog: 20p13Molecular Function: protein bindingBiological Process: proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; protein ubiquitination during ubiquitin-dependent protein catabolic process
UniProt Protein Details:
NCBI Summary:
This gene encodes an integral membrane protein that contains a RING-type zinc finger. The encoded protein may interact with multiple transient receptor potential cation channel subfamily C (TRPC) proteins and regulate the trafficking and insertion of these proteins into the plasma membrane. [provided by RefSeq, Mar 2016]
