The RNF220 Polyclonal Antibody (CAB15853) is a valuable tool for researchers studying the RNF220 protein, a crucial player in the regulation of cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the RNF220 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology, cell biology, and cancer research.RNF220, also known as a E3 ubiquitin-protein ligase, plays a pivotal role in protein degradation and signaling pathways within cells. Its functions in protein turnover and cellular signaling make it a promising target for research into various diseases, including cancer, neurodegenerative disorders, and metabolic conditions.
Understanding the mechanisms of action of RNF220 is essential for developing targeted therapies that can manipulate cellular processes in disease contexts.Overall, the RNF220 Polyclonal Antibody (CAB15853) is a valuable tool for scientists looking to delve deeper into the role of RNF220 in cellular processes and disease mechanisms. Its specificity and sensitivity make it an indispensable asset for studies aiming to uncover new insights into the functions and potential therapeutic targets associated with RNF220.
Product Name:
RNF220 Rabbit Polyclonal Antibody
SKU:
CAB15853
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 267-566 of human RNF220 (NP_060620.2).
Predicted to enable ubiquitin protein ligase activity. Involved in positive regulation of canonical Wnt signaling pathway. Part of protein-containing complex.
Purification Method:
Affinity purification
Gene ID:
55182
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using RNF220 Rabbit pAb (CAB15853) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
