The RNF214 Polyclonal Antibody (PACO17006) is a valuable tool for researchers studying the RNF214 protein, a key player in various cellular processes including protein degradation and DNA repair. This antibody, produced in rabbits, is highly specific to human RNF214 and has been validated for use in Western blot applications.RNF214, also known as Ring finger protein 214, is involved in the regulation of cell growth and survival, making it an important target for studies in cancer research and developmental biology.
By detecting and analyzing RNF214 protein levels in different cell types, researchers can gain insights into its function and potential role in disease progression.The RNF214 Polyclonal Antibody is a reliable tool for exploring the complex pathways involving RNF214 and its interactions with other proteins. Its high specificity and sensitivity make it an ideal choice for researchers looking to further understand the molecular mechanisms underlying various cellular processes.
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-4: 823 cells, PC3 cells, 231 cells, hepg2 cells, Primary antibody: PACO17006(RNF214 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds.
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17006(RNF214 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200).
Background:
RNF214 (RING finger protein 214) is a 703 amino acid, protein that contains one RING-type zinc finger and is encoded by a gene that maps to human chromosome 11q23.3. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
Synonyms:
ring finger protein 214
UniProt Protein Function:
RNF214: 2 isoforms of the human protein are produced by alternative splicingProtein type: Ubiquitin conjugating systemChromosomal Location of Human Ortholog: 11q23.3Molecular Function: zinc ion binding
