RING1B/RNF2 Rabbit Polyclonal Antibody (CAB5563)
- SKU:
- CAB5563
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- IF
- IP
- ChIP
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | RING1B/RNF2 Rabbit Polyclonal Antibody |
SKU: | CAB5563 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-336 of human RING1B/RING1B/RNF2 (NP_009143.1). |
Sequence: | MSQA VQTN GTQP LSKT WELS LYEL QRTP QEAI TDGL EIVV SPRS LHSE LMCP ICLD MLKN TMTT KECL HRFC ADCI ITAL RSGN KECP TCRK KLVS KRSL RPDP NFDA LISK IYPS RDEY EAHQ ERVL ARIN KHNN QQAL SHSI EEGL KIQA MNRL QRGK KQQI ENGS GAED NGDS SHCS NAST HSNQ EAGP SNKR TKTS DDSG LELD NNNA AMAI DPVM DGAS EIEL VFRP HPTL MEKD DSAQ TRYI KTSG NATV DHLS KYLA VRLA LEEL RSKG ESNQ MNLD TASE KQYT IYIA TASG QFTV LNGS FSLE LVSE KYWK VNKP MELY YAPT KEHK |
Tested Applications: | WB IHC-P IF/ICC IP ChIP ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cellsChIP,5μg antibody for 10μg-15μg of Chromatin |
Synonyms: | BAP1; DING; BAP-1; HIPI3; RING2; LUSYAM; RING1B; RING1B/RNF2 |
Positive Sample: | Jurkat |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus. |
Calculated MW: | 38kDa |
Observed MW: | 41kDa |
Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.
Purification Method: | Affinity purification |
Gene ID: | 6045 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |