The RNF183 Polyclonal Antibody (PAC02952) is a valuable tool for researchers studying the RNF183 protein, which is involved in various cellular processes such as protein degradation and immune regulation. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications.RNF183, also known as a ubiquitin ligase, plays a crucial role in regulating protein turnover and immune responses. Its involvement in these processes makes it a promising target for research in fields such as immunology and cancer biology. By binding to the RNF183 protein, this antibody allows for the detection and analysis of RNF183 expression in different cell types, providing valuable insights for understanding its function and potential therapeutic implications.
Researchers interested in exploring the role of RNF183 in diseases like cancer, autoimmune disorders, and inflammatory conditions will find this antibody to be a valuable tool in their studies. By investigating the activity of RNF183, researchers can gain a deeper understanding of its impact on cellular pathways and potentially uncover new strategies for therapeutic intervention.
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO29552 at dilution of 1:100.
Immunofluorescent analysis of HepG2 cells using PACO29552 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Synonyms:
E3 ubiquitin-protein ligase RNF183, RNF183
UniProt Protein Function:
RNF183: Protein type: Ubiquitin conjugating system; Membrane protein, integralChromosomal Location of Human Ortholog: 9q32Molecular Function: protein binding
