The RNF182 Monoclonal Antibody (PACO38270) is a versatile tool for researchers studying RNF182, a protein involved in the ubiquitination process and cellular signaling pathways. This antibody, produced using hybridoma technology, specifically targets human samples and is suitable for use in various experimental applications, including Western blot, immunoprecipitation, and immunofluorescence.RNF182, a member of the RING finger protein family, plays a key role in protein degradation and turnover by tagging proteins with ubiquitin molecules. This process is crucial for maintaining cellular homeostasis and regulating various biological processes.
By targeting RNF182, researchers can gain insights into the mechanisms underlying protein degradation and identify potential therapeutic targets for diseases characterized by aberrant protein turnover.The RNF182 Monoclonal Antibody is an essential tool for investigating the functions of RNF182 in cellular physiology and pathophysiology. Its high specificity and sensitivity make it suitable for a wide range of research applications, making it an invaluable asset for researchers in the fields of molecular biology, cell biology, and protein science.
RNF182: E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway.Protein type: Ubiquitin ligase; EC 6.3.2.-; Ligase; EC 6.3.2.19; Membrane protein, integral; Membrane protein, multi-pass; Ubiquitin conjugating systemChromosomal Location of Human Ortholog: 6p23Cellular Component: cytoplasm; integral to membraneMolecular Function: ligase activity; protein binding; ubiquitin-protein ligase activity; zinc ion bindingBiological Process: protein ubiquitination
