The RNF181 Polyclonal Antibody (CAB14405) is a valuable tool for researchers studying the RNF181 protein, a member of the RING finger protein family involved in ubiquitination and protein degradation processes. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, and has been validated for use in Western blot applications.RNF181 is known to play a role in various cellular processes, including cell cycle regulation, DNA repair, and signal transduction pathways. Its dysregulation has been linked to diseases such as cancer, neurodegenerative disorders, and autoimmune diseases.
By using the RNF181 Polyclonal Antibody, researchers can detect and analyze the expression of RNF181 in different cell types, aiding in the understanding of its function and potential as a therapeutic target.With its proven efficacy in Western blotting assays, the RNF181 Polyclonal Antibody is a reliable tool for investigating the biological functions of RNF181 in both normal and disease states. Whether in the field of cancer research, neurology, or immunology, this antibody is a valuable asset for scientists seeking to unravel the complexities of cellular processes involving the RNF181 protein.
Product Name:
RNF181 Rabbit Polyclonal Antibody
SKU:
CAB14405
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-153 of human RNF181 (NP_057578.1).
RNF181 binds the integrin alpha-IIb (ITGA2B; MIM 607759)/beta-3 (ITGB3; MIM 173470) complex and has E3 ubiquitin ligase activity (Brophy et al., 2008 [PubMed 18331836]).
Purification Method:
Affinity purification
Gene ID:
51255
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RNF181 Rabbit pAb (CAB14405) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
