The RNF180 Polyclonal Antibody (CAB15241) is a valuable tool for researchers studying the RNF180 protein, which plays a key role in various cellular processes. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding to the RNF180 protein, this antibody allows for the detection and analysis of RNF180 in different cell types, making it ideal for studies in molecular biology and disease research.
RNF180, also known as Ring Finger Protein 180, is a ubiquitin ligase that regulates protein degradation and signaling pathways within cells. Its involvement in these pathways makes it a target of interest for researchers studying diseases such as cancer, neurodegenerative disorders, and metabolic conditions. Understanding the function of RNF180 is crucial for developing targeted therapies that can manipulate cellular processes for therapeutic benefit.
Product Name:
RNF180 Rabbit Polyclonal Antibody
SKU:
CAB15241
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-416 of human RNF180 (NP_848627.1).
Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in norepinephrine metabolic process; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; and serotonin metabolic process. Predicted to act upstream of or within several processes, including adult behavior; positive regulation of protein ubiquitination; and protein polyubiquitination. Predicted to be located in nuclear envelope. Predicted to be integral component of membrane. Predicted to be intrinsic component of endoplasmic reticulum membrane.
Purification Method:
Affinity purification
Gene ID:
285671
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RNF180 Rabbit pAb (CAB15241) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
