RNF170 Rabbit Polyclonal Antibody (CAB15195)
- SKU:
- CAB15195
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | RNF170 Rabbit Polyclonal Antibody |
SKU: | CAB15195 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 46-120 of human RNF170 (NP_001153696.1). |
Sequence: | RNVH QNIH PENQ ELVR VLRE QLQT EQDA PAAT RQQF YTDM YCPI CLHQ ASFP VETN CGHL FCGA CIIA YWRY GSW |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ADSA; SNAX1; SPG85; RNF170 |
Positive Sample: | Mouse thymus,Mouse brain,Mouse pancreas |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Multi-pass membrane protein. |
Calculated MW: | 30kDa |
Observed MW: | 30kDa |
This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 81790 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |