RNF149 Polyclonal Antibody (CAB24526)
- SKU:
- CAB24526
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IF
Description
RNF149 Polyclonal Antibody (CAB24526)
The RNF149 Polyclonal Antibody is a valuable tool for researchers studying the function of RNF149, a protein involved in immune regulation and cellular processes. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the RNF149 protein, this antibody allows for the detection and analysis of RNF149 in various cell types, making it an ideal choice for studies in immunology and cancer research.RNF149, also known as a key regulator of protein stability, plays a crucial role in maintaining cellular homeostasis and controlling protein levels.
The importance of RNF149 in cellular processes underscores its potential as a target for research into diseases such as cancer, neurodegenerative disorders, and metabolic conditions. By elucidating the function of RNF149, researchers can gain insights into disease mechanisms and potentially identify novel therapeutic strategies for various conditions.
Product Name: | RNF149 Polyclonal Antibody |
Product Code: | CAB24526 |
Reactivity: | Human, Rat |
Applications: | Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Rat |
Tested Applications: | IF/ICC, ELISA |
Key Applications: | Immunofluorescence |
Recommended Dilution: | IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Cellular Location: | cytoplasm |
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within cellular response to xenobiotic stimulus; negative regulation of MAPK cascade; and regulation of protein stability. Located in membrane.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human RNF149(NP_775918.2). |
Sequence: | SVVFV AIAFI TMMII SLAWL IFYYI QRFLY TGSQI GSQSH RKETK KVIGQ LLLHT VKHGE KGIDV DAENC AVCIE NFKVK DIIRI LPCKH IFHRI CIDPW L |
Synonyms: | RNF149, DNAPTP2, ring finger protein 149 |
Calculated MW: | 43kDa |
Observed MW: | Refer to figures |