The RNF149 Polyclonal Antibody (CAB15627) is an essential tool for researchers studying RNF149, a gene involved in immune regulation and protein degradation pathways. This antibody, produced through immunization of rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By binding to the RNF149 protein, this antibody allows for precise detection and analysis in various cell types, making it ideal for studies in immunology and cancer research.RNF149, a RING finger protein, plays a crucial role in the maintenance of cellular homeostasis by mediating protein ubiquitination and degradation.
Its involvement in regulating immune responses and protein turnover makes it a promising target for research into diseases such as cancer, autoimmune disorders, and neurodegenerative conditions. Investigating the function of RNF149 is essential for the development of novel therapeutic strategies aimed at modulating immune responses and protein stability in disease contexts.
Product Name:
RNF149 Rabbit Polyclonal Antibody
SKU:
CAB15627
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 221-400 of human RNF149 (NP_775918.2).
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within cellular response to xenobiotic stimulus; negative regulation of MAPK cascade; and regulation of protein stability. Located in membrane.
Purification Method:
Affinity purification
Gene ID:
284996
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse stomach using RNF149 Rabbit pAb(CAB15627) at 1:600 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime:30s.
