The RNF138 Polyclonal Antibody (CAB10304) is a valuable tool for research involving RNF138, a protein involved in the regulation of protein degradation and turnover. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the RNF138 protein, this antibody enables accurate detection and analysis in various cell types, making it an excellent choice for studies in the fields of molecular biology and cancer research.
RNF138, a member of the RING finger protein family, plays a crucial role in controlling the stability and function of key proteins within the cell. Its involvement in protein degradation pathways makes it a potential target for therapeutic interventions in diseases like cancer, where abnormal protein turnover can contribute to tumorigenesis. By studying the function of RNF138, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new strategies for treatment.
Product Name:
RNF138 Rabbit Polyclonal Antibody
SKU:
CAB10304
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-245 of mouse RNF138 (Q9CQE0).
Predicted to enable protein kinase binding activity; single-stranded DNA binding activity; and ubiquitin protein ligase activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in chromosome. Predicted to be active in site of double-strand break. Is expressed in several structures, including genitourinary system; lung; nervous system; sensory organ; and tooth. Orthologous to human RNF138 (ring finger protein 138).
Purification Method:
Affinity purification
Gene ID:
56515
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of BT-474 cells, using RNF138 antibody (CAB10304) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
