The RNF125 Polyclonal Antibody (CAB15166) is specifically designed for research involving RNF125, a crucial regulator of immune response and protein degradation processes. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the RNF125 protein, this antibody allows for the detection and analysis of RNF125 in various cell types, making it an ideal tool for studies in immunology and cancer research.RNF125, also known as E3 ubiquitin-protein ligase RNF125, plays a vital role in the regulation of immune signaling pathways and the degradation of key signaling molecules.
Its involvement in immune regulation and protein turnover processes makes it a valuable target for research into diseases such as cancer, autoimmune disorders, and inflammatory conditions. Understanding the function of RNF125 is essential for the development of novel therapeutic strategies that target immune dysregulation in these diseases.Overall, the RNF125 Polyclonal Antibody (CAB15166) offers researchers a reliable tool for studying the role of RNF125 in immune regulation and protein degradation processes, paving the way for advancements in immunotherapy and treatment strategies for immune-related diseases.
Product Name:
RNF125 Rabbit Polyclonal Antibody
SKU:
CAB15166
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-105 of human RNF125 (NP_060301.2).
This gene encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. As a result of myristoylation, this protein associates with membranes and is primarily localized to intracellular membrane systems. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway.
Purification Method:
Affinity purification
Gene ID:
54941
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RNF125 Rabbit pAb (CAB15166) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
