The RNF125 Polyclonal Antibody (CAB15165) is a potent tool for researchers studying RNF125, a protein involved in the regulation of immune responses and cellular functions. Produced in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blotting applications. By binding to the RNF125 protein, this antibody allows for the detection and analysis of RNF125 in various cell types, making it an essential reagent for studies in immunology and cancer research.RNF125, a ubiquitin ligase, plays a crucial role in the degradation of certain proteins involved in immune signaling pathways, making it a key player in the regulation of inflammatory responses and immune system function.
Understanding the functions of RNF125 is vital for unraveling its potential role in diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. By targeting RNF125, researchers may uncover new therapeutic strategies for modulating immune responses and treating various immune-related disorders.
Product Name:
RNF125 Rabbit Polyclonal Antibody
SKU:
CAB15165
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 41-200 of human RNF125 (NP_060301.2).
This gene encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. As a result of myristoylation, this protein associates with membranes and is primarily localized to intracellular membrane systems. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway.
Purification Method:
Affinity purification
Gene ID:
54941
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using RNF125 Rabbit pAb (CAB15165) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
