The RNF115 Polyclonal Antibody (CAB17687) is a valuable tool for researchers studying RNF115, a protein involved in protein degradation and cellular regulation. This antibody, produced in rabbits, exhibits high specificity and sensitivity in detecting RNF115 in human samples, particularly in Western blot applications. By binding to the RNF115 protein, this antibody enables precise detection and quantification, making it an essential component for studies in cellular biology and protein degradation pathways.RNF115, also known as E3 ubiquitin-protein ligase RNF115, plays a crucial role in targeting specific proteins for degradation via the ubiquitin-proteasome system.
Its involvement in cellular protein turnover makes it an attractive target for research in various fields, including oncology and neurodegenerative diseases. Understanding the function and regulation of RNF115 can provide valuable insights into disease mechanisms and potential therapeutic targets for drug development.Overall, the RNF115 Polyclonal Antibody (CAB17687) offers researchers a reliable tool for investigating the biological functions of RNF115 and its role in disease pathogenesis. Its high specificity and sensitivity make it a valuable asset for studies aiming to unravel the complexities of cellular regulation and protein degradation pathways.
Product Name:
RNF115 Rabbit Polyclonal Antibody
SKU:
CAB17687
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-140 of human RNF115 (NP_055270.1).
Enables ubiquitin-protein transferase activity. Involved in negative regulation of epidermal growth factor receptor signaling pathway; protein autoubiquitination; and ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to be located in cytosol.
Purification Method:
Affinity purification
Gene ID:
27246
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat brain, using RNF115 Rabbit pAb (CAB17687) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
