The RNF11 Polyclonal Antibody (CAB8328) is a valuable tool for researchers studying RNF11, a protein involved in regulating various cellular processes. This antibody, generated in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the RNF11 protein, it allows for accurate detection and analysis in a variety of cell types, making it ideal for investigations in cell signaling and protein degradation pathways.RNF11 is known to play a role in diverse biological functions, including cell growth, differentiation, and immune responses. Its involvement in protein ubiquitination and degradation processes highlights its importance in maintaining cellular homeostasis.
Research into RNF11 can provide insights into the mechanisms underlying diseases such as cancer, neurodegenerative disorders, and immune-related conditions.By utilizing the RNF11 Polyclonal Antibody, researchers can delve into the intricate functions of RNF11 and its impact on cellular physiology. This antibody serves as a reliable tool for studying the molecular pathways associated with RNF11, paving the way for novel therapeutic approaches and enhancing our understanding of various disease processes.
Product Name:
RNF11 Rabbit Polyclonal Antibody
SKU:
CAB8328
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-154 of human RNF11 (NP_055187.1).
Cytoplasm, Early endosome, Nucleus, Recycling endosome.
Calculated MW:
17kDa
Observed MW:
27kDa
The protein encoded by this gene contains a RING-H2 finger motif, which is known to be important for protein-protein interactions. The expression of this gene has been shown to be induced by mutant RET proteins (MEN2A/MEN2B). The germline mutations in RET gene are known to be responsible for the development of multiple endocrine neoplasia (MEN).
Purification Method:
Affinity purification
Gene ID:
26994
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RNF11 antibody (CAB8328) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
