RNASEH2B Rabbit Polyclonal Antibody (CAB4972)
- SKU:
- CAB4972
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- RNASEH2B
- AGS2
- DLEU8
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | RNASEH2B Rabbit Polyclonal Antibody |
SKU: | CAB4972 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human RNASEH2B (NP_078846.2). |
Sequence: | MAAG VDCG DGVG ARQH VFLV SEYL KDAS KKMK NGLM FVKL VNPC SGEG AIYL FNMC LQQL FEVK VFKE KHHS WFIN QSVQ SGGL LHFA TPVD PLFL LLHY LIKA DKEG KFQP LDQV VVDN VFPN CILL LKLP GLEK LLHH VTEE KGNP EIDN KKYY KYSK EKTL KWLE KKVN QTVA ALKT NNVN VSSR VQST AFFS GDQA STDK EEDY IRYA HGLI SDYI PKEL SDDL SKYL KLPE PSAS LPNP PSKK IKLS DEPV EAKE DYTK FNTK DLKT EKKN SKMT AAQK ALAK VD |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | AGS2; DLEU8; RNASEH2B |
Positive Sample: | A-431,Raji,K-562,HeLa,MCF-7,Mouse thymus,Rat thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 35kDa |
Observed MW: | 37kDa |
RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2).
Purification Method: | Affinity purification |
Gene ID: | 79621 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |