RNASEH1 Rabbit Polyclonal Antibody (CAB9116)
- SKU:
- CAB9116
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | RNASEH1 Rabbit Polyclonal Antibody |
SKU: | CAB9116 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-286 of human RNASEH1 (NP_002927.2). |
Sequence: | MSWL LFLA HRVA LAAL PCRR GSRG FGMF YAVR RGRK TGVF LTWN ECRA QVDR FPAA RFKK FATE DEAW AFVR KSAS PEVS EGHE NQHG QESE AKAS KRLR EPLD GDGH ESAE PYAK HMKP SVEP APPV SRDT FSYM GDFV VVYT DGCC SSNG RRRP RAGI GVYW GPGH PLNV GIRL PGRQ TNQR AEIH AACK AIEQ AKTQ NINK LVLY TDSM FTIN GITN WVQG WKKN GWKT SAGK EVIN KEDF VALE RLTQ GMDI QWMH VPGH SGFI GNEE ADRL AREG AKQS ED |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | RNH1; H1RNA; PEOB2; RNASEH1 |
Positive Sample: | Mouse testis,Rat thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 32kDa |
Observed MW: | 37kDa |
This gene encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and plays a key role in DNA replication and repair. Alternate in-frame start codon initiation results in the production of alternate isoforms that are directed to the mitochondria or to the nucleus. The production of the mitochondrial isoform is modulated by an upstream open reading frame (uORF). Mutations in this gene have been found in individuals with progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 2. Alternative splicing results in additional coding and non-coding transcript variants. Pseudogenes of this gene have been defined on chromosomes 2 and 17.
Purification Method: | Affinity purification |
Gene ID: | 246243 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |