The RMI2 Polyclonal Antibody (CAB8523) is a valuable tool for researchers studying RMI2, a protein involved in DNA repair and maintenance. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding to the RMI2 protein, this antibody allows for the detection and analysis of RMI2 in various cell types, making it ideal for studies in molecular biology and cancer research.RMI2, also known as RecQ-mediated genome instability protein 2, is essential for stabilizing DNA structures and promoting genomic integrity. Dysregulation of RMI2 has been linked to mutations and chromosomal abnormalities associated with cancer and other genetic disorders.
Understanding the function of RMI2 is crucial for developing targeted therapies that can correct DNA damage and prevent disease progression.Overall, the RMI2 Polyclonal Antibody (CAB8523) offers researchers a reliable tool for investigating the role of RMI2 in DNA repair pathways and its potential implications for human health. Its specificity and sensitivity make it a valuable asset for advancing our understanding of genome stability and potential therapeutic interventions.
Product Name:
RMI2 Rabbit Polyclonal Antibody
SKU:
CAB8523
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human RMI2 (NP_689521.1).
RMI2 is a component of the BLM (RECQL3; MIM 604610) complex, which plays a role in homologous recombination-dependent DNA repair and is essential for genome stability (Xu et al., 2008 [PubMed 18923082]).
Purification Method:
Affinity purification
Gene ID:
116028
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RMI2 antibody (CAB8523) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
