RLN3 Antibody (PACO03409)
- SKU:
- PACO03409
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
RLN3 Antibody (PACO03409)
The RLN3 Polyclonal Antibody (PACO3409) is a valuable tool for researchers studying RLN3, a neuropeptide that plays a crucial role in regulating various physiological processes. The antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the RLN3 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in neuroscience, endocrinology, and reproductive biology.RLN3, also known as Relaxin-3, is involved in modulating stress responses, feeding behavior, and reproductive function.
Its diverse roles in the body make it a promising target for research into conditions such as anxiety disorders, obesity, and infertility. Investigating the function of RLN3 could provide valuable insights into potential therapeutic strategies for these and other related health issues.Overall, the RLN3 Polyclonal Antibody (PACO3409) offers researchers a reliable tool for exploring the complex functions of RLN3 and its implications for human health. Its specificity and sensitivity make it a valuable asset for studies aiming to unravel the intricacies of neuroendocrine signaling and its impact on various biological processes.
| Antibody Name: | RLN3 Antibody |
| Antibody SKU: | PACO03409 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | IHC:1:100-1:300 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the Internal region of human Relaxin 3. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | RLN3; INSL7; RXN3; ZINS4; Relaxin-3; Insulin-like peptide INSL7; Insulin-like peptide 7; Prorelaxin H3 |
| UniProt Protein Function: | RLN3: May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142). Belongs to the insulin family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: extracellular region Molecular Function:protein binding; G-protein-coupled receptor binding; hormone activity |
| NCBI Summary: | Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. The protein encoded by this gene is a member of the relaxin family. The active form of the encoded protein consists of an A chain and a B chain but their cleavage sites are not definitely described yet. It may play a role in neuropeptide signaling processes. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8WXF3 |
| NCBI GenInfo Identifier: | 37999891 |
| NCBI Gene ID: | 117579 |
| NCBI Accession: | Q8WXF3.1 |
| UniProt Secondary Accession: | Q8WXF3,Q6UXW5, |
| UniProt Related Accession: | Q8WXF3 |
| Molecular Weight: | 15,451 Da |
| NCBI Full Name: | Relaxin-3 |
| NCBI Synonym Full Names: | relaxin 3 |
| NCBI Official Symbol: | RLN3 |
| NCBI Official Synonym Symbols: | H3; RXN3; ZINS4; insl7 |
| NCBI Protein Information: | relaxin-3; prorelaxin H3; insulin-like 7; insulin-like peptide 7; insulin-like peptide INSL7 |
| UniProt Protein Name: | Relaxin-3 |
| UniProt Synonym Protein Names: | Insulin-like peptide INSL7; Insulin-like peptide 7; Prorelaxin H3Cleaved into the following 2 chains:Relaxin-3 B chain; Relaxin-3 A chain |
| Protein Family: | Relaxin |
| UniProt Gene Name: | RLN3 |
| UniProt Entry Name: | REL3_HUMAN |
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