RLIM Rabbit Polyclonal Antibody (CAB15837)
- SKU:
- CAB15837
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | RLIM Rabbit Polyclonal Antibody |
SKU: | CAB15837 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 535-624 of human RLIM (NP_057204.2). |
Sequence: | FLLN EDDD DQPR GLTK EQID NLAM RSFG ENDA LKTC SVCI TEYT EGNK LRKL PCSH EYHV HCID RWLS ENST CPIC RRAV LASG NRES VV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | MRX61; RNF12; TOKAS; NY-REN-43; RLIM |
Positive Sample: | Raji,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 69kDa |
Observed MW: | 75kDa |
The protein encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Purification Method: | Affinity purification |
Gene ID: | 51132 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |