The RLIM Polyclonal Antibody (CAB15837) offered by AssayGenie is a valuable tool for researchers studying the RLIM protein, a crucial player in gene regulation and cellular processes. This antibody, produced using rabbits, demonstrates high reactivity with human samples and is optimized for Western blot applications.RLIM, also known as Ring finger protein LIM domain-interacting, is a critical regulator of gene expression and plays a key role in various cellular functions, including cell growth, differentiation, and apoptosis.
By targeting the RLIM protein, researchers can gain insights into its function and impact on cellular pathways.Whether studying developmental biology, cancer research, or gene regulation, the RLIM Polyclonal Antibody is a reliable choice for detecting and analyzing the RLIM protein in various cell types. Its specificity and sensitivity make it an invaluable tool for advancing scientific understanding in these fields.
Product Name:
RLIM Rabbit Polyclonal Antibody
SKU:
CAB15837
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 535-624 of human RLIM (NP_057204.2).
The protein encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Purification Method:
Affinity purification
Gene ID:
51132
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RLIM Rabbit pAb (CAB15837) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 150s.
