The RLBP1 Polyclonal Antibody (CAB9094) is a vital tool for researchers studying RLBP1, a protein involved in the visual cycle and retinoid metabolism. This antibody, generated in rabbits, exhibits high specificity for human and mouse samples, and is validated for use in various applications including immunohistochemistry and Western blotting.RLBP1, also known as retinaldehyde-binding protein 1, plays a crucial role in the transport and storage of retinoids in the eye, essential for maintaining vision and protecting photoreceptor cells.
Dysregulation of RLBP1 has been linked to various retinal diseases, making it a promising target for therapeutic interventions.By utilizing the RLBP1 Polyclonal Antibody, researchers can accurately detect and quantify RLBP1 levels in different cellular and tissue samples, aiding in the understanding of its function and potential implications in retinal disorders. This antibody is a valuable tool for advancing research in ophthalmology and vision-related conditions.
Product Name:
CRALBP Rabbit Polyclonal Antibody
SKU:
CAB9094
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-317 of human CRALBP (NP_000317.1).
The protein encoded by this gene is a 36-kD water-soluble protein which carries 11-cis-retinaldehyde or 11-cis-retinal as physiologic ligands. It may be a functional component of the visual cycle. Mutations of this gene have been associated with severe rod-cone dystrophy, Bothnia dystrophy (nonsyndromic autosomal recessive retinitis pigmentosa) and retinitis punctata albescens.
Purification Method:
Affinity purification
Gene ID:
6017
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CRALBP antibody (CAB9094) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
