The RipPLY2 Polyclonal Antibody (PACO60108) is a powerful tool for researchers studying RipPLY2, a key protein involved in cell signaling pathways. This antibody, produced in rabbits, has been extensively tested and validated for use in Western blot applications with human samples. It specifically targets the RipPLY2 protein, allowing for precise detection and analysis in a variety of cell types.RipPLY2 is a critical player in cellular processes such as proliferation, differentiation, and survival, making it a valuable target for studies in molecular biology and cancer research.
By understanding the role of RipPLY2 in these processes, researchers can gain insights into the mechanisms underlying disease development and progression.Overall, the RipPLY2 Polyclonal Antibody is an essential tool for researchers looking to unravel the intricate functions of RipPLY2 and its implications in various biological pathways. Its high specificity and reliability make it an ideal choice for studies aiming to uncover new therapeutic targets in cancer and other diseases.
Antibody Name:
RIPPLY2 Antibody (PACO60108)
Antibody SKU:
PACO60108
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:200-1:500
Species Reactivity:
Human
Immunogen:
Recombinant Human Protein ripply2 protein (1-76AA)
IHC image of PACO60108 diluted at 1:200 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Background:
Plays a role in somitogenesis. Required for somite segregation and establishment of rostrocaudal polarity in somites (By similarity).
Synonyms:
Protein ripply2, RIPPLY2, C6orf159
UniProt Protein Function:
RIPPLY2: Plays a role in somitogenesis. Required for somite segregation and establishment of rostrocaudal polarity in somites. Belongs to the ripply family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 6q14.2Cellular Component: nucleusBiological Process: ossification; Notch signaling pathway; somitogenesis; regulation of gene expression; determination of left/right symmetry; somite rostral/caudal axis specification
