The RIPK4 Polyclonal Antibody (CAB8495) is a valuable tool for researchers studying the RIPK4 protein, a crucial regulator of cell death and inflammation. This antibody, produced in rabbits, exhibits high reactivity towards human samples and is specifically validated for use in Western blot applications. By binding to the RIPK4 protein, it enables precise detection and analysis in a variety of cell types, making it perfect for investigations in the fields of immunology and cancer research.RIPK4, also known as receptor-interacting serine/threonine-protein kinase 4, is a key player in signaling pathways that control immune responses and inflammatory processes.
Its involvement in cell death mechanisms and inflammation regulation make it a promising target for exploring diseases such as cancer, autoimmune disorders, and inflammatory conditions. Understanding the functions of RIPK4 is essential for the development of targeted therapies that can manipulate these processes for therapeutic purposes.
Product Name:
RIPK4 Rabbit Polyclonal Antibody
SKU:
CAB8495
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 240-520 of human RIPK4 (NP_065690.2).
The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation.
Purification Method:
Affinity purification
Gene ID:
54101
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from A375 cells, using RIPK4 Rabbit pAb (CAB8495) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
