RIPK3 Rabbit Polyclonal Antibody (CAB5431)
- SKU:
- CAB5431
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | RIPK3 Rabbit Polyclonal Antibody |
SKU: | CAB5431 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant Protein corresponding to a sequence within amino acids 21-287 of human RIP3 (NP_006862.2). |
Sequence: | LENQ ELVG KGGF GTVF RAQH RKWG YDVA VKIV NSKA ISRE VKAM ASLD NEFV LRLE GVIE KVNW DQDP KPAL VTKF MENG SLSG LLQS QCPR PWPL LCRL LKEV VLGM FYLH DQNP VLLH RDLK PSNV LLDP ELHV KLAD FGLS TFQG GSQS GTGS GEPG GTLG YLAP ELFV NVNR KAST ASDV YSFG ILMW AVLA GREV ELPT EPSL VYEA VCNR QNRP SLAE LPQA GPET PGLE GLKE LMQL CWSS EPKD RPSF QECL PKTD EVF |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | RIP3; RIPK3 |
Positive Sample: | HeLa(Negative control),L929 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Mitochondrion, cytosol. |
Calculated MW: | 57kDa |
Observed MW: | 57kDa/46-62kDa(M) |
The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
Purification Method: | Affinity purification |
Gene ID: | 11035 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |