RIPK1/RIP Rabbit Monoclonal Antibody (CAB19580)
- SKU:
- CAB19580
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | RIPK1/RIP Rabbit Monoclonal Antibody |
SKU: | CAB19580 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 289-490 of human RIPK1/RIP (NP_003795.2). |
Sequence: | YLSQ LEES VEED VKSL KKEY SNEN AVVK RMQS LQLD CVAV PSSR SNSA TEQP GSLH SSQG LGMG PVEE SWFA PSLE HPQE ENEP SLQS KLQD EANY HLYG SRMD RQTK QQPR QNVA YNRE EERR RRVS HDPF AQQR PYEN FQNT EGKG TAYS SAAS HGNA VHQP SGLT SQPQ VLYQ NNGL YSSH GFGT RPLD PGTA GPRV WY |
Tested Applications: | WB IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | RIP; RIP1; AIEFL; IMD57; RIP-1; RIPK1/RIP |
Positive Sample: | Raji,HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm. |
Calculated MW: | 76kDa |
Observed MW: | 75kDa |
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth.
Purification Method: | Affinity purification |
Gene ID: | 8737 |
Clone Number: | ARC0059 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |