RIPK1/RIP Rabbit Polyclonal Antibody (CAB7414)
- SKU:
- CAB7414
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | RIPK1/RIP Rabbit Polyclonal Antibody |
SKU: | CAB7414 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human RIPK1/RIP (NP_003795.2). |
Sequence: | LMHV LKAE MSTP LSVK GRII LEII EGMC YLHG KGVI HKDL KPEN ILVD NDFH IKIA DLGL ASFK MWSK LNNE EHNE LREV DGTA KKNG GTLY YMAP EHLN D |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | RIP; RIP1; AIEFL; IMD57; RIP-1; RIPK1/RIP |
Positive Sample: | Raji,Jurkat,Mouse liver,C6 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm. |
Calculated MW: | 76kDa |
Observed MW: | 75kDa/38kDa |
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth.
Purification Method: | Affinity purification |
Gene ID: | 8737 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |