RING1B/RNF2 Rabbit Monoclonal Antibody (CAB3564)
- SKU:
- CAB3564
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | RING1B/RNF2 Rabbit Monoclonal Antibody |
SKU: | CAB3564 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human RING1B/RNF2 (Q99496). |
Sequence: | LRPD PNFD ALIS KIYP SRDE YEAH QERV LARI NKHN NQQA LSHS IEEG LKIQ AMNR LQRG KKQQ IENG SGAE DNGD SSHC SNAS THSN QEAG PSNK RTKT S |
Tested Applications: | WB IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | BAP1; DING; BAP-1; HIPI3; RING2; LUSYAM; RING1B; RING1B/RNF2 |
Positive Sample: | THP-1,U-937,Mouse testis,Mouse spleen,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus. |
Calculated MW: | 38kDa |
Observed MW: | 38kDa |
Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.
Purification Method: | Affinity purification |
Gene ID: | 6045 |
Clone Number: | ARC0802 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |