The RING1B/RNF2 Rabbit Monoclonal Antibody (CAB3564) is a highly specific antibody designed for research involving the RING1B/RNF2 protein, a key player in the regulation of gene expression and chromatin structure. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications such as Western blot and immunohistochemistry.The RING1B/RNF2 protein is a member of the polycomb group proteins that play a critical role in epigenetic regulation and transcriptional repression. It is involved in diverse cellular processes such as cell differentiation, development, and cancer progression.
The RING1B/RNF2 Rabbit Monoclonal Antibody enables the detection and analysis of RING1B/RNF2 protein levels in different cell types, making it an invaluable tool for studies in molecular biology, cancer research, and epigenetics.Understanding the function and regulation of RING1B/RNF2 protein is essential for deciphering its role in various biological processes and disease pathways. This antibody provides researchers with a reliable and specific tool for investigating the mechanisms underlying RING1B/RNF2-mediated gene regulation, offering new insights into potential therapeutic targets for cancer and other diseases.
Product Name:
RING1B/RNF2 Rabbit Monoclonal Antibody
SKU:
CAB3564
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human RING1B/RNF2 (Q99496).
Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.
Purification Method:
Affinity purification
Gene ID:
6045
Clone Number:
ARC0802
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using RING1B/RNF2 Rabbit mAb (CAB3564) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
