RNF7 Rabbit Polyclonal Antibody (CAB7301)
- SKU:
- CAB7301
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | RNF7 Rabbit Polyclonal Antibody |
SKU: | CAB7301 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-113 of human RNF7 (NP_055060.1). |
Sequence: | MADV EDGE ETCA LASH SGSS GSKS GGDK MFSL KKWN AVAM WSWD VECD TCAI CRVQ VMDA CLRC QAEN KQED CVVV WGEC NHSF HNCC MSLW VKQN NRCP LCQQ DWVV QRIG K |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:20 - 1:50 |
Synonyms: | SAG; ROC2; rbx2; CKBBP1; RNF7 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 13kDa |
Observed MW: | Refer to figures |
The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Purification Method: | Affinity purification |
Gene ID: | 9616 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |