The RIN3 Polyclonal Antibody (PACO11845) is a valuable tool for researchers studying RIN3, a key protein involved in cellular signaling pathways and membrane trafficking. This antibody, generated in rabbits, exhibits high specificity towards human samples and has been validated for use in Western blot applications. By targeting the RIN3 protein, this antibody enables the detection and analysis of RIN3 in a variety of cell types, making it an excellent choice for studies in cell biology and molecular biology.RIN3 is known to play a crucial role in regulating intracellular trafficking processes, such as endocytosis and membrane recycling, which are essential for maintaining cellular function and homeostasis.
Dysfunction of RIN3 has been implicated in various diseases, including neurological disorders and cancer, highlighting its potential as a therapeutic target. By studying the function of RIN3, researchers can gain valuable insights into the underlying mechanisms of disease and identify novel strategies for treatment and intervention.
Ras and Rab interactor 3;RIN3;DKFZp762H1613;FLJ11700;FLJ22439 ;
UniProt Protein Function:
Ras effector protein that functions as a guanine nucleotide exchange (GEF) for RAB5B and RAB31, by exchanging bound GDP for free GTP. Required for normal RAB31 function.
UniProt Protein Details:
NCBI Summary:
Summary: This protein encoded by this gene is a member of the RIN family of Ras interaction-interference proteins, which are binding partners to the RAB5 small GTPases. The protein functions as a guanine nucleotide exchange for RAB5B and RAB31. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
