RIN2 Rabbit Polyclonal Antibody (CAB13798)
- SKU:
- CAB13798
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | RIN2 Rabbit Polyclonal Antibody |
SKU: | CAB13798 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 596-895 of human RIN2 (NP_061866.1). |
Sequence: | HKCI LKPL KGHV EAML KDFH MADG SWKQ LKEN LQLV RQRN PQEL GVFA PTPD FVDV EKIK VKFM TMQK MYSP EKKV MLLL RVCK LIYT VMEN NSGR MYGA DDFL PVLT YVIA QCDM LELD TEIE YMME LLDP SLLH GEGG YYLT SAYG ALSL IKNF QEEQ AARL LSSE TRDT LRQW HKRR TTNR TIPS VDDF QNYL RVAF QEVN SGCT GKTL LVRP YITT EDVC QICA EKFK VGDP EEYS LFLF VDET WQQL AEDT YPQK IKAE LHSR PQPH IFHF VYKR IKND PYGI IFQN GEED LTTS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | MACS; RASSF4; RIN2 |
Positive Sample: | 293T,A-549,HeLa,HepG2,Mouse heart,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 100kDa |
Observed MW: | 120kDa |
The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 54453 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |