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Rig-I/DDX58 Polyclonal Antibody

SKU:
CAB21421
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
IHC
IF
€129 - €359
Frequently bought together:

Description

Product Name:Rig-I/DDX58 Polyclonal Antibody
Product Code:CAB21421
Reactivity:Human, Mouse
Applications:Western blotting, Immunohistochemistry, Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human, Mouse
Tested Applications:WB, IHC-P, IF/ICC, ELISA
Key Applications:Western blotting, Immunohistochemistry, Immunofluorescence
Recommended Dilution:WB 1:500-1:2000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Positive Samples:Jurkat, HepG2, MCF7
Cellular Location:Cell junction, Cell projection, Cytoplasm, cytoskeleton, ruffle membrane, tight junction

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 825-925 of human Rig-I/DDX58. (NP_055129.2).
Sequence:VIEEC HYTVL GDAFK ECFVS RPHPK PKQFS SFEKR AKIFC ARQNC SHDWG IHVKY KTFEI PVIKI ESFVV EDIAT GVQTL YSKWK DFHFE KIPFD PAEMS K
Synonyms:RIG1, DDX58, RIG-I, RLR-1, SGMRT2
Calculated MW:107kDa
Observed MW:Refer to figures

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