Rig-I/DDX58 Monoclonal Antibody (CAB22478)
- SKU:
- CAB22478
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | Rig-I/DDX58 Monoclonal Antibody |
SKU: | CAB22478 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 241-455 of human Rig-I/DDX58 (NP_055129.2). |
Sequence: | FKPR NYQL ELAL PAMK GKNT IICA PTGC GKTF VSLL ICEH HLKK FPQG QKGK VVFF ANQI PVYE QQKS VFSK YFER HGYR VTGI SGAT AENV PVEQ IVEN NDII ILTP QILV NNLK KGTI PSLS IFTL MIFD ECHN TSKQ HPYN MIMF NYLD QKLG GSSG PLPQ VIGL TASV GVGD AKNT DEAL DYIC KLCA SLDA SVIA TVKH NLEE LEQV VYK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | RIG1; DDX58; RIG-I; RLR-1; SGMRT2; Rig-I/DDX58 |
Positive Sample: | THP-1,RAW264.7 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell projection, Cytoplasm, cytoskeleton, ruffle membrane, tight junction. |
Calculated MW: | 107kDa |
Observed MW: | 107kDa |
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2.
Purification Method: | Affinity purification |
Gene ID: | 23586 |
Clone Number: | ARC54110 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |