Ribosome-inactivating protein cucurmosin Antibody (PACO34042)
The Ribosome Inactivating Protein Cucurmosin Antibody (PACO34042) is a high-quality polyclonal antibody designed for research involving Cucurmosin, a ribosome-inactivating protein with potential anti-tumor and anti-viral properties. The antibody, produced in rabbits, exhibits high reactivity with samples from various species and is validated for use in Western blotting and immunohistochemistry applications. By specifically binding to the Cucurmosin protein, this antibody allows for precise detection and analysis in different cell types, making it an essential tool for studies in cancer research and virology.
Cucurmosin, a type I ribosome-inactivating protein found in the seeds of pumpkins, has shown promising cytotoxic effects against tumor cells and has been explored for its potential in cancer therapy. Additionally, its antiviral properties have sparked interest in investigating its role in combating viral infections. The Cucurmosin Antibody enables researchers to study the mechanisms of action and the therapeutic potential of this unique protein, furthering our understanding of its applications in cancer treatment and antiviral strategies.
Antibody Name:
Ribosome-inactivating protein cucurmosin Antibody (PACO34042)
Antibody SKU:
PACO34042
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Cucurbita moschata
Immunogen:
Recombinant Cucurbita moschata Ribosome-inactivating protein cucurmosin protein (1-244AA)
Western Blot. Positive WB detected in: Cucurbita moschata (40μg, 20μg, 10μg, 5μg). All lanes: rRNA N-glycosidase antibody at 4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 28 kDa. Observed band size: 28 kDa.
Background:
Has cytotoxic activity towards cancer cells, but not normal cells. Inhibits the growth of the human leukemia cell line K562, the murine melanoma cell line B16 and the lung adenocarcinoma cell line A549 with IC(50) values of 88.1 nM, 63.4 nM and 359.3 nM respectively.
Synonyms:
Ribosome-inactivating protein cucurmosin (EC 3.2.2.22) (rRNA N-glycosidase)
UniProt Protein Function:
Has cytotoxic activity towards cancer cells, but not normal cells. Inhibits the growth of the human leukemia cell line K562, the murine melanoma cell line B16 and the lung adenocarcinoma cell line A549 with IC50 values of 88.1 nM, 63.4 nM and 359.3 nM respectively.
