The RHOU Polyclonal Antibody (CAB17195) is a valuable tool for researchers studying the RHOU protein, a member of the Rho family of GTPases involved in cell signaling and cytoskeletal organization. This antibody, generated in rabbits, is specifically designed for use in Western blot applications and is highly reactive with human samples.RHOU plays a crucial role in various cellular processes, including cell migration, polarity, and proliferation. Its dysregulation has been implicated in cancer progression, making it an important target for cancer research. By binding to the RHOU protein, this antibody allows for the detection and analysis of RHOU expression in different cell types, providing valuable insights into its function in normal and disease states.
With its versatility and specificity, the RHOU Polyclonal Antibody is an excellent tool for researchers in the fields of cell biology, cancer biology, and signal transduction. By studying the expression and activity of RHOU, scientists can gain a better understanding of its role in cellular processes and potentially uncover new therapeutic targets for cancer and other diseases.
Product Name:
RHOU Rabbit Polyclonal Antibody
SKU:
CAB17195
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 40-100 of human RHOU (NP_067028.1).
This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.
Purification Method:
Affinity purification
Gene ID:
58480
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse stomach, using RHOU Rabbit pAb (CAB17195) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
