The RHOU Polyclonal Antibody (CAB17194) is a valuable tool for researchers studying the RHOU protein, a member of the Rho family of GTPases known for its role in regulating cell migration and adhesion. This antibody, produced in rabbits, exhibits high specificity and sensitivity in detecting RHOU in human samples, making it suitable for use in Western blot applications.RHOU is involved in various cellular processes, including cytoskeletal organization and cell motility, making it a key target for studying cancer metastasis and cell invasion. The RHOU Polyclonal Antibody enables precise detection and analysis of RHOU expression in different cell types, providing insights into its function in normal physiological processes and disease states.
Researchers in the fields of cell biology, cancer research, and drug development will find the RHOU Polyclonal Antibody essential for their studies on cell migration, invasion, and metastasis. By unraveling the molecular mechanisms by which RHOU influences these processes, this antibody contributes to advancing our understanding of cancer biology and may ultimately lead to the development of targeted therapies for cancer treatment.
Product Name:
RHOU Rabbit Polyclonal Antibody
SKU:
CAB17194
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 40-100 of human RHOU (NP_067028.1).
This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.
Purification Method:
Affinity purification
Gene ID:
58480
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from U-87MG cells, using RHOU Rabbit pAb (CAB17194) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
