The Rhombotin 2 Polyclonal Antibody (CAB1903) is a key tool for researchers studying Rhombotin 2, a transcription factor that plays a critical role in hematopoiesis, or the formation of blood cells. This antibody, raised in rabbits, is highly specific to human Rhombotin 2 and is validated for use in immunostaining and Western blot applications. It binds specifically to Rhombotin 2, allowing for accurate detection and analysis in a variety of cell types.Rhombotin 2 is known for its involvement in the development and differentiation of blood cells, making it a crucial factor in understanding diseases such as leukemia and lymphoma.
By studying the role of Rhombotin 2, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets. The Rhombotin 2 Polyclonal Antibody is a valuable tool for furthering our understanding of hematopoiesis and its implications for human health.
Product Name:
LMO2 Rabbit Polyclonal Antibody
SKU:
CAB1903
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-158 of human LMO2 (NP_001135788.1).
LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
4005
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LMO2 Rabbit pAb (CAB1903) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
