The RHOBTB2 Polyclonal Antibody (CAB18432) is a valuable tool for researchers studying RHOBTB2, a protein involved in cellular processes such as protein transport and regulation of the cell cycle. This rabbit-derived antibody is highly specific to human samples and has been validated for use in Western blot applications.RHOBTB2, also known as Rho-related BTB domain-containing protein 2, is a key player in various cellular functions, including cell migration, proliferation, and differentiation. Its role in maintaining cell homeostasis and regulating signaling pathways makes it a promising target for studies in cell biology and cancer research.
By targeting the RHOBTB2 protein, this antibody allows for the detection and analysis of RHOBTB2 expression in different cell types, providing insights into its function and potential implications in disease states. Understanding the molecular mechanisms involving RHOBTB2 is essential for uncovering novel therapeutic strategies for diseases like cancer and neurological disorders.
Product Name:
RHOBTB2 Rabbit Polyclonal Antibody
SKU:
CAB18432
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 320-480 of human RHOBTB2 (NP_001153508.1).
The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
23221
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat lung, using RHOBTB2 Rabbit pAb (CAB18432) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
