RHOBTB1/RHOBTB2 Antibody (PACO01431)
- SKU:
- PACO01431
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
RHOBTB1/RHOBTB2 Antibody (PACO01431)
The RHOBTB1/RHOBTB2 Antibody (PAC01431) is a high-quality polyclonal antibody designed for research involving RHOBTB1 and RHOBTB2 proteins. These proteins are critical regulators of cell signaling pathways, specifically involved in cell proliferation, migration, and apoptosis. The antibody, produced in rabbits, is highly specific and reactive with human samples, making it suitable for use in Western blot and immunohistochemistry applications.RHOBTB1 and RHOBTB2 are important players in cancer biology, with their dysregulation implicated in tumorigenesis and metastasis. Studying the expression and function of these proteins can provide valuable insights into cancer progression and potential therapeutic targets.
The RHOBTB1/RHOBTB2 Antibody enables precise detection and analysis of these proteins in various cell types, making it an ideal tool for researchers in the fields of oncology and cell biology.The antibody's reliability and specificity make it an essential tool for studies aiming to elucidate the role of RHOBTB1 and RHOBTB2 in cellular processes and disease pathogenesis. By understanding the functions and interactions of these proteins, researchers can uncover novel molecular mechanisms underlying cancer development and progression, paving the way for innovative therapeutic strategies targeting RHOBTB1 and RHOBTB2.
| Antibody Name: | RHOBTB1/RHOBTB2 Antibody |
| Antibody SKU: | PACO01431 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | synthesized peptide derived from the N-terminal region of human RhoBTB1/2. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | RHOBTB1; KIAA0740; Rho-related BTB domain-containing protein 1; RHOBTB2; DBC2; KIAA0717; Rho-related BTB domain-containing protein 2; Deleted in breast cancer 2 gene protein; p83 |
| UniProt Protein Function: | RHOBTB1: belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008] |
| UniProt Protein Details: | Protein type:G protein, monomeric; G protein, monomeric, Rho; G protein Chromosomal Location of Human Ortholog: 10q21.2 Cellular Component: cytosol; plasma membrane Biological Process: regulation of small GTPase mediated signal transduction |
| NCBI Summary: | The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008] |
| UniProt Code: | O94844 |
| NCBI GenInfo Identifier: | 26006842 |
| NCBI Gene ID: | 9886 |
| NCBI Accession: | O94844.2 |
| UniProt Related Accession: | O94844 |
| Molecular Weight: | 79,417 Da |
| NCBI Full Name: | Rho-related BTB domain-containing protein 1 |
| NCBI Synonym Full Names: | Rho related BTB domain containing 1 |
| NCBI Official Symbol: | RHOBTB1Â Â |
| NCBI Protein Information: | rho-related BTB domain-containing protein 1 |
| UniProt Protein Name: | Rho-related BTB domain-containing protein 1 |
| Protein Family: | Rho-related BTB domain-containing protein |
| UniProt Gene Name: | RHOBTB1Â Â |
| UniProt Entry Name: | RHBT1_HUMAN |
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