The RHOBTB1 Polyclonal Antibody (CAB9959) is a valuable tool for researchers studying RHOBTB1, a protein involved in various cellular processes, including cell migration, proliferation, and signal transduction. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.RHOBTB1, a member of the Rho GTPase family, is known to play a role in regulating cytoskeleton dynamics and controlling cell cycle progression. Dysregulation of RHOBTB1 has been implicated in various diseases, including cancer and neurodegenerative disorders.
By targeting RHOBTB1 with this antibody, researchers can investigate its function and potential therapeutic implications in these pathologies.With its specificity and sensitivity in detecting RHOBTB1, the CAB9959 antibody is a valuable tool for studies in cell biology, cancer research, and neurobiology. By enabling the detection and analysis of RHOBTB1 protein expression in various cell types, this antibody facilitates a deeper understanding of the molecular mechanisms underlying disease pathogenesis and opens up new avenues for therapeutic interventions.
Product Name:
RHOBTB1 Rabbit Polyclonal Antibody
SKU:
CAB9959
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 240-400 of human RHOBTB1 (NP_055651.1).
The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
9886
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RHOBTB1 antibody (CAB9959) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
