The RhoB Polyclonal Antibody (CAB2819) is a valuable tool for researchers studying the RhoB protein, a member of the Rho GTPase family involved in cell signaling and cytoskeletal dynamics. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blotting applications. By binding to RhoB, this antibody allows for the detection and analysis of RhoB expression in various cell types.RhoB plays a crucial role in cellular processes such as cell migration, cell adhesion, and cell cycle regulation. Dysregulation of RhoB has been implicated in cancer progression, making it an attractive target for cancer research.
Additionally, RhoB has been implicated in other diseases such as cardiovascular disorders and neurological conditions, making it a promising candidate for further study.By using the RhoB Polyclonal Antibody (CAB2819), researchers can gain valuable insights into the function and regulation of RhoB in various physiological and pathological contexts. This antibody is a valuable tool for advancing our understanding of RhoB's role in health and disease, ultimately paving the way for the development of novel therapeutic strategies targeting RhoB.
Product Name:
RhoB Rabbit Polyclonal Antibody
SKU:
CAB2819
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-190 of human RhoB (NP_004031.1).
Cell membrane, Cleavage furrow, Late endosome membrane, Lipid-anchor, Nucleus.
Calculated MW:
22kDa
Observed MW:
21kDa
Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Involved in several processes, including cellular response to hydrogen peroxide; cellular response to ionizing radiation; and regulation of cell migration. Located in cleavage furrow and endosome membrane. Biomarker of breast cancer.
Purification Method:
Affinity purification
Gene ID:
388
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of Rat lung, using RhoB Rabbit pAb antibody (CAB2819) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
